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What is BPC-157 Peptide?

BPC-157, also known as Body Protection Compound-157, is a synthetic peptide derived from a protein found in human gastric juice. It is known for its regenerative properties and potential therapeutic effects on various tissues and organs.

BPC-157 has been extensively studied for its ability to promote tissue healing, reduce inflammation, improve blood flow and gut health.

This peptide is commonly used in Hungary research settings and has gained attention for its potential to accelerate muscle and tendon healing, protect the gastrointestinal tract, and support overall well-being. 

Molecular Formula: C62H98N16O22

Sequence: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH

Molecular Weight: 1419.5 g/mol

View the HPLC Certificate here.

Source: PubChem


Summary of BPC-157 Benefits:

Buy BPC-157 Peptide Vial Hungary here for laboratory research use – Available in 2mg, 5mg & 10mg

BPC-157 Mechanism of Action

Hungary Clinical studies have found that when administered, BPC-157 interacts with different biological pathways becoming a regenerative medicine to promote healing and recovery in various tissues and organs.

One key mechanism of BPC-157 is its ability to stimulate the formation of new blood vessels, a process known as angiogenesis. By enhancing blood vessel growth, the BPC-157 peptide has been shown to improve blood flow to damaged or inflamed areas, facilitating the delivery of oxygen and nutrients essential for tissue repair [1].

Moreover, BPC-157 has been shown to modulate inflammatory responses by reducing the levels of pro-inflammatory molecules and promoting the release of anti-inflammatory cytokines. This anti-inflammatory action helps alleviate tissue damage and supports the healing process.

Additionally, BPC-157 exhibits antioxidant properties, which can protect cells from oxidative stress and free radical damage, further aiding in tissue regeneration. It may also stimulate the expression of growth factors that play a role in tissue repair and regeneration.

Overall, Hungary scientists believe that BPC-157 works through a combination of angiogenic, anti-inflammatory, and antioxidant mechanisms to promote healing, reduce inflammation, and support overall tissue health and well-being.

Buy BPC-157 Nasal Spray from PharmaLabGlobal Hungary for research purposes. Offering a non-invasive, peptide nasal delivery to your clinical research.

Buy BPC-157 peptide

Potential Clinical Applications of BPC-157 Peptide

BPC-157, is a synthetic peptide derived from a protein in the gastric juice of humans. With further Hungary clinical research, scientists hope it could hold potential therapeutic benefits and eventually be approved for human consumption for the following applications:

Healing Wounds

The natural purpose of BPC in the GI tract is to protect the mucosal barrier from damaging effects of stomach acid, bile, and other substances essential for digestion and nutrient absorption. This function is mediated by fibroblast activation. BPC 157 increases the proliferation and migration of fibroblasts in vitro and in vivo. In wound healing, fibroblasts play a significant role because they are the cells that make extracellular matrix proteins such as collagen and fibrin [1]. In addition, they also make elastin and other proteins. Furthermore, the BPC-157 research chemical has also proved useful when treating skin burns helping reduce scarring [2].

Tendon Repair

It’s no surprise that BPC-157 has shown promise in treating ligament, tendon, bone, and other connective tissue injuries in animal models. Tendon and ligament injuries heal slowly due to insufficient blood flow. Poor blood flow hinders the arrival of fibroblasts and other wound-healing cells, limiting the overall level of repair. In rat tendons, BPC-157 enhances collateralization and increases fibroblast density in vitro and in vivo studies. Additionally BPC157 appears to be more effective than EFG, bFGF, and VGF hormones in encouraging tissue repair and overall joint health [3].

Collateralization and Vascular Growth

BPC 157 is an effective angiogenic factor, enhancing the rate of endothelial cell proliferation and growth. Hungary Animal studies showed the peptide accelerates collateral blood vessel development in ischemia. BPC-157 may be employed as both a therapeutic peptide for stroke and heart attack and a probative peptide for learning how to enhance recovery after ischemic injury.

Studies in chicken embryos suggest that BPC 157 stimulates vascular development by activating VEGFR2, a cell surface receptor involved in nitric oxide signalling. VEGFR2 may be involved in endothelial cell development, proliferation, and lifespan [5].

Antioxidant Functions

BPC-157 has been demonstrated to reduce nitric oxide and malondialdehyde (MDA) levels in rat studies. According to studies, a potent antioxidant, BPC-157, has been shown to inhibit reactive oxygen species generation in the gastrointestinal system. BPC-157 levels in cells cultured with modified Lactococcus lactis bacteria grow substantially.

Drug Reactions

BPC-157 has been shown to reduce the adverse effects of NSAIDs, psychiatric drugs, and several cardiac treatments. BPC-157 also protects the brain, heart, and other tissues from side effects. For example, studies on rats reveal that BPC-157 can protect against QTc prolongation, which can cause significant and even fatal arrhythmias. Pharmaceuticals used to treat diabetes, schizophrenia, and other psychiatric diseases cause QTc prolongation. Similarly, BPC157 has been demonstrated to reduce psychiatric medication side effects such as catalepsy and sensorimotor disturbance [6].

Gastrointestinal Protection

BPC-157 has shown promise in protecting the gastrointestinal tract due to its ability to promote healing and mitigate damage within the digestive system. This synthetic peptide exhibits gastroprotective properties by enhancing the repair of mucosal tissues, reducing inflammation, and regulating the secretion of gastric acid. By stimulating the production of new blood vessels and supporting tissue regeneration, BPC-157 can help heal gastric ulcers, counteract damage from inflammatory bowel diseases, and maintain the integrity of the gastrointestinal lining including mitigating leaky gut [4]. These actions contribute to the overall health of the digestive tract, with more research, making BPC-157 a potential therapeutic option for gastrointestinal conditions.

Buy BPC-157 Pre-Mixed Peptide Pen. Pen kits and pre-mixed refill cartridges supplied by PharmaLabGlobal Hungary for research purposes.

Is BPC-157 useful for healing bone fractures?

By stimulating the formation of new blood vessels (angiogenesis), promoting collagen production, and enhancing the growth of various cell types involved in bone repair, BPC-157 may support the overall healing process of bone fractures. Additionally, its anti-inflammatory properties and ability to reduce oxidative stress could help  bone healing.

BPC-157 FAQ's

Is BPC-157 Safe?

BPC-157 has shown a generally favourable safety profile in research studies and anecdotal reports, with limited adverse effects reported when used at appropriate dosages. It is considered well-tolerated by many individuals, especially when administered under medical supervision. However, it is yet to be approved by the FDA for human consumption. 

Does BPC-157 help with nerve damage?

BPC-157 has shown promising potential in aiding nerve damage recovery due to its regenerative properties and ability to promote healing processes. While research on BPC-157’s specific effects on nerve damage is ongoing, some Hungary studies suggest that this peptide may support nerve regeneration, reduce inflammation, and improve overall tissue repair, which could be beneficial for individuals with nerve injuries or damage.

Does BPC-157 help with inflammation?

BPC-157 is known for its anti-inflammatory properties and has been studied for its potential to reduce inflammation in various tissues throughout the body. By modulating the immune response and inhibiting inflammatory processes, BPC-157 may help alleviate inflammation associated with injuries, digestive disorders, and other inflammatory conditions.

BPC-157 VIP Peptide Stack

Buy BPC-157 & VIP Peptide Combo

Combining BPC-157 peptide with VIP (Vasoactive Intestinal Peptide) peptide can create a powerful synergy in promoting overall wellness and healing.

BPC-157’s regenerative properties, known for repairing tissues and reducing inflammation, complement VIP peptide’s role in supporting immune function, reducing oxidative stress, and enhancing cellular repair.

Together, they can potentially amplify the healing process, especially in conditions involving gut health, musculoskeletal injuries, and general recovery.

BPC-157 focuses on tissue repair and gut health, while VIP peptide contributes to immune modulation and cellular rejuvenation. According to research this combined approach may offer comprehensive benefits such as faster recovery from injuries, improved gastrointestinal function, reduced inflammation, and enhanced overall well-being.

Buy BPC-157 VIP Peptide Combo here.

Scientific Research

[1] Huang T, Zhang K, Sun L, Xue X, Zhang C, Shu Z, Mu N, Gu J, Zhang W, Wang Y, Zhang Y, Zhang W. Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro. Drug Des Devel Ther. 2015 Apr 30;9:2485-99. 

[2] Gwyer D, Wragg NM, Wilson SL. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell Tissue Res. 2019 Aug;377(2):153-159.

[3] Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. J Appl Physiol (1985). 2011 Mar;110(3):774-80. 

[4] Duzel A, Vlainic J, Antunovic M, Malekinusic D, Vrdoljak B, Samara M, Gojkovic S, Krezic I, et al. Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights. World J Gastroenterol. 2017 Dec 28;23(48):8465-8488. 

[5] Grabarevic Z, Tisljar M, Artukovic B, Bratulic M, Dzaja P, Seiwerth S, Sikiric P, Peric J, Geres D, Kos J. The influence of BPC 157 on nitric oxide agonist and antagonist induced lesions in broiler chicks. J Physiol Paris. 1997 May-Oct;91(3-5):139-49.

[6] Škrlec K, Ručman R, Jarc E, Sikirić P, Švajger U, Petan T, Perišić Nanut M, Štrukelj B, Berlec A. Engineering recombinant Lactococcus lactis as a delivery vehicle for BPC-157 peptide with antioxidant activities. Appl Microbiol Biotechnol. 2018 Dec;102(23):10103-10117. 

Further Reading:

Below are a selection of posts focusing on BPC-157. For further reading, explore our main Blog Page here.

Understanding the Synergistic Effects of KPV and BPC-157 Peptide Combination

Discover how this unique combination works together to enhance tissue repair, reduce inflammation, and accelerate the healing process. Researchers are investigating the synergistic effects of the KPV and BPC-157 peptide combo could be the key to unlocking enhanced recovery outcomes.

Find out how BPC-157 and KPV can be so effective.

BPC-157 Peptide for Accelerated Healing

Find out how BPC-157 aids in tissue regeneration, reduces inflammation, and promotes overall healing of injuries. We delve into the science behind this remarkable peptide, looking at its mechanisms of action, and the various applications in which it can be beneficial for accelerating healing, from muscle strains to joint injuries. 

Discover why BPC-157 is excellent for accelerating healing.

Oral Shipment of Drugs Barriers & Advancements

Explore the various barriers that oral drug shipments face, from degradation in the digestive system to limited absorption, and discover the latest advancements in technology and formulation strategies that aim to overcome these obstacles. 

Find out more about the oral bioavailability of peptides and which ones are the most efficient here.

Why Buy BPC-157 from PharmaLabGlobal?

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Peptides are manufactured to a purity standard of 99% (complex peptides are 98% pure or higher)

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